Lumiprobe DBCO NHS ester
  • Lumiprobe DBCO NHS ester

DBCO NHS ester

¥1,330.00
含13%增值税(专票和普票价格相同)
包装规格
数量
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IUPAC name: 6-{2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanamide

Solubility: good in DCM, DMF, DMSO

Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain promoted alkyne azide cycloaddition (spAAC) – a copper free Click chemistry reaction.

This is an amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.

DBCO reacts instantly with azides. The rate of the reaction is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines - this allows to carry out orthogonal conjugation of azides with DBCO, and trans-cyclooctenes with tetrazines.

二苯并环辛炔(ADIBO,DBCO)是用于应变促进的炔叠氮化物环加成反应(spAAC)(一种无铜点击化学反应)的最具反应性的环炔烃之一。

这是一种胺反应性NHS酯,可将反应性部分轻松连接至几乎任何伯或仲胺基团,例如蛋白质,肽或小分子胺基团。

DBCO瞬间与叠氮化物反应。该反应速率远高于铜催化的反应速率以及与许多其他环辛炔的反应速率。与其他某些环辛炔不同,DBCO不与四嗪发生反应-这使得叠氮化物与DBCO和反式环辛烯与四嗪进行正交共轭。

44720

详细信息

保存温度
冷冻 (-20C)
CAS #
1384870-47-6
分子式
C25H22N2O5
分子量
430.45
外观
off white solid
产地
美国

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DBCO NHS ester说明书

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