GeneSilencer siRNA Transfection Reagent,siRNA转染试剂



Brand : Genlantis

  • High siRNA transfection efficiency

  • Functional gene silencing post siRNA delivery

  • Compatibility with diverse growth conditions (with and without serum)

  • Low cytotoxicity

  • Easy-to-use protocols for both adherent and suspension cells

GeneSilencer siRNA Transfection Reagent, siRNA转染试剂
GeneSilencer® siRNA Transfection Reagent is a novel cationic lipid formulation specifically designed for efficient delivery of siRNAs (small interfering RNAs) into a wide variety of cell types. siRNAs are short,gene-specific double-stranded RNAs that can cause gene silencing in mammalian cells by catalytically cleaving greater than 95% of the target mRNA (1,2,3). 


  • Hydrated GeneSilencer Lipid
  • siRNA Diluent (corresponding ratio for each kit)


GeneSilencer siRNA Transfection Reagent is shipped at room temperature,as similar to other gene therapy products. For maximum stability,store all reagents at 4ºC upon receipt. If stored properly,all components are stable for 6 months.

GeneSilencer Transfection Reagent Kit订购信息

  • 50 rxn kit,0.18 ml,T500020
  • 200 rxn kit,0.75 ml,T500750
  • 1000 rxn kit,5 x 0.75 ml,T505750
  • 10 rxn sample kit,0.03 ml,T500020S
New Citations

Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization. 
Li,D.,et al (2018) Cancer Res. 78 (5): 1169-1183. Link

Apoptotic cells trigger the ABCA1/STAT6 pathway leading to PPAR-γ expression and activation in macrophages.
Kim,M-J.,et al (2018) J. Leukocyte Biol. 103(5): 885-895. Link

Transient Silencing of DNA Repair Genes Improves Targeted Gene Integration in the Filamentous Fungus Trichoderma reesei.
Chum,P.Y.,et al ((2017) Appl. Environ. Microbiol. 83(15): e00535-17. Link

Programming of macrophages by apoptotic cancer cells inhibits cancer progression through exosomal PTEN and PPARγ ligands.
Kim,Y-B.,et al (2017) bioRxiv 217562: 1-75. Link

Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium.
Fu,P.,et al (2016) J. Biol. Chem. 291(53): 27187–27203. Link

Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.
Jean-Charles,P-Y.,(2016) J. Biol. Chem. 291 (14): 7450 –7464. Link

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2.
Yeste,A.,et al (2016) Sci. Signal. 9(433): RA61. Link

Synthesis of an Endogenous Steroidal Na Pump Inhibitor Marinobufagenin,Implicated in Human Cardiovascular Diseases,Is Initiated by CYP27A1 via Bile Acid Pathway.
Fedorova,O.V.,et al (2015) Circ Cardiovasc Genet. 8(5): 736-45. Link

Thioredoxin Activates MKK4-NFκB Pathway in a Redox-dependent Manner to Control Manganese Superoxide Dismutase Gene Expression in Endothelial Cells.
Kundumani-Sridharan,V.,et al (2015) J. Biol. Chem. 290(28): 17505–17519. Link

Identification,Mechanism of Action,and Antitumor Activity of a Small Molecule Inhibitor of Hippo,TGF-β,and Wnt Signaling Pathways.
Basu,D.,et al (2014) Mol. Cancer Ther. 13(6): 1457-1467. Link

PKC Potentiates Tyrosine Kinase Inhibitors STI571 and Dasatinib Cytotoxic Effect.
TobÍo,A.,et al (2014) Anticancer Res. 34(7): 3347-3356. Link

TREK2 Expressed Selectively in IB4-Binding C-Fiber Nociceptors Hyperpolarizes Their Membrane Potentials and Limits Spontaneous Pain.
Acosta,C.,et al (2014) J. Neurosci. 34(4): 1494-1509. Link

RhoA/Phosphatidylinositol 3-Kinase/Protein Kinase B/Mitogen-Activated Protein Kinase Signaling after Growth Arrest–Specific Protein 6/Mer Receptor Tyrosine Kinase Engagement Promotes Epithelial Cell Growth and Wound Repair via Upregulation of Hepatocyte Growth Factor in Macrophages.
Lee,Y-J.,et al (2014) J. Pharma. Exp. Thera. 350(3): 563-577. Link

GeneSilencer Cell Line Citations: 3T3-L1,A549,A7,AGS,ASM Transformed,B16-F1,BEL7404,Bronchial C166,C2C12,C6R,CHO-K1,DC2.4,GS-KB-3-1,H22,H441,H460,H9c2,hCMEC/D3,HCP40,HCT-116,HEK 293,HEK 293T,HEK-293,HeLa,HepG2,HL-60,HMEC-1,HPAEC,HT29,HUT-78,JAR,Jurkat,KATOIII,L/Stab-2,LNCaP,M2,McA-RH 7777,MCF-7,MDA MB-231,MDA MB-468,MDA-MB-435,MG63,MKN 28,MKN 45,MV-4-11,Neuro2a,NIH-3T3,OK,PC-12,Cortical Neurons,Hippocampal Neurons,Macrophage,Pulmonary Artery,Endothelium,Dendritic Cells(Bone Marrow),Cortical Neurons,Coronary Artery Endothelial,Peritoneal Macrophage,Dorsal Root Ganglion Neurons,Retinal Ganglion,Dorsal Root Ganglion,Schwann Cells Cardiac Fibroblast,Cardiac Myocytes (Neonatal),Lung Microvascular Endothelial Cells,Aortic Muscle Cells,Dendritic Cells,Cerebellar Neurons,Osteoblast,HMVEC,Cardiac Myocytes,T-Cells (CD3+),Cortical Neurons,Dendritic Cells,Cortical Neurons,Aveolar Type II Cells,Macrophage,Dorsal Root Ganglion Lacrimal Gland Acinar Cells,Bone Marrow,Dendritic Cells,Pulmonary Artery Endothelium,Primary HPAEC. RAW 264.7,Renca,SaOs2,Saos-2,SCCH196,SNB19,SW480,U20S